In vitro Antioxidant Activity on Roots of Limnophila Heterophylla

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Abstract
Free Radicals and Antioxidants,2016,6,2,178-185.
Published:January 2016
Type:Original Article
Authors:
Author(s) affiliations:

Raja Sundararajan* and Ravindranadh Koduru

Department of Pharmaceutical Chemistry, GITAM Institute of Pharmacy, GITAM University, Visakhapatnam-530045, Andhra Pradesh, INDIA.

Abstract:

Objective: The present study was investigating the antioxidant activity of methanol extract of roots of Limnophila heterophylla (Plantaginaceae). Methods: Roots of methanol extract of Limnophila heterophylla were tested for in vitro free radical scavenging assays, such as hydroxyl radical, antioxidant assay by thiocyanate method, inhibition of superoxide anion radical, 2, 2-diphenyl-1-picryl hydrazyl radical (DPPH), lipid peroxidation assay, scavenging of 2, 2’- azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) diammonium salt radical cation assay (ABTS), total antioxidant activity (phosphomolybdic acid method) and reducing ability. Results: Limnophila heterophylla roots extract effectively scavenged free radicals at all different concentrations and showed its potent antioxidant activity. Further, these effects were in a dose dependent manner. Results were compared to standard antioxidants such as vitamin E, α-tocopherol, curcumin, quercetin, rutin, butylated hydroxytoluene (BHT), and ascorbic acid. Conclusion: Limnophila heterophylla enclose strong antioxidant potential. Further the study validates the therapeutic benefits of the Indian system of medicine.

Cite This Article

Vancouver Style :: Sundararajan R, Koduru R. In vitro Antioxidant Activity on Roots of Limnophila Heterophylla. Free Radicals and Antioxidants. 2016;6(2):178-185.  (288.08 KB)
MLA Style: Sundararajan R, Koduru R. In vitro Antioxidant Activity on Roots of Limnophila Heterophylla. Free Radicals and Antioxidants. 2016;6(2):178-185.  (288.08 KB)
CSE Style: Sundararajan R, Koduru R. In vitro Antioxidant Activity on Roots of Limnophila Heterophylla. Free Radicals and Antioxidants. 2016;6(2):178-185.  (288.08 KB)
APA Style: Sundararajan R, Koduru R. In vitro Antioxidant Activity on Roots of Limnophila Heterophylla. Free Radicals and Antioxidants. 2016;6(2):178-185.  (288.08 KB)