Antimicrobial and Antioxidant Activities of Polyphenols against Streptococcus mutans

Authors

  • Varunraj Sendamangalam Department of Chemical & Environmental Engineering, University of Toledo, Toledo, OH 43606,
  • One Kyun Choi Department of Chemical & Environmental Engineering, University of Toledo, Toledo, OH 43606,
  • Youngwoo Seo 1Department of Chemical & Environmental Engineering, University of Toledo, Toledo, OH 43606, 2Department of Civil Engineering, University of Toledo, Toledo, OH 43606,
  • Don-Shik Kim Department of Chemical & Environmental Engineering, University of Toledo, Toledo, OH 43606,

DOI:

https://doi.org/10.5530/ax.2011.3.7

Keywords:

ABTS method, DMPD method, MIC

Abstract

Natural polyphenols, gallic acid, tannic acid, quercetin and salicylic acid, were investigated for their antimicrobial and antioxidant activities against Streptococcus mutans. Ascorbic acid, well known for its antimicrobial and antioxidant activities, was used as a criterion for the polyphenols. The antimicrobial effect was assessed using the plate dilution assay and the minimum inhibitory concentration (MIC) of each polyphenol was then determined from the antimicrobial activity results. Salicylic acid was the weakest antimicrobial with the highest MIC (3.8 mg/mL), and tannic acid was the strongest antimicrobial with the lowest MIC of 0.4 mg/mL. Antioxidant capacities were evaluated using the DMPD and ABTS decolorizing assays. These polyphenols show high antimicrobial activity and inoxidizability. Antioxidant activity for quercetin according to the DMPD method was inconclusive because it had color interference with the DMPD radicals. Although some conflicting results were observed between the DMPD and ABTS methods, the polyphenols with high antioxidant capacities still showed high antimicrobial activities, which suggest that the antioxidant capacity attributes to the antimicrobial effects.

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Comparison of the antioxidant capacities and antimicrobial activities of the polyphenols

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Published

2020-12-11

How to Cite

Sendamangalam, V. ., Kyun Choi, O. ., Seo, Y., & Kim, D.-S. . (2020). Antimicrobial and Antioxidant Activities of Polyphenols against Streptococcus mutans. Free Radicals and Antioxidants, 1(3), 48–55. https://doi.org/10.5530/ax.2011.3.7