@article{I. Abdelhady_A. H. Aly_2020, title={Antioxidant and Antimicrobial Activities of Callistemon comboynensis Essential Oil}, volume={2}, url={https://antiox.org/index.php/fra/article/view/251}, DOI={10.5530/ax.2012.2.8}, abstractNote={<p><strong>Introduction:</strong> The genus <em>Callistemon</em> is known in folk medicine for its anticough, antibronchitis, and insecticidal effects and its volatile oils have been used as antimicrobial and antifungal agents. Methods: The essential oils obtained by hydrodistillation of the leaves of <em>Callistemon comboynensis</em> (<em>Cc</em>) was investigated by GC/MS. Antioxidant activity of<em> Cc</em> was investigated using 1,1-diphenyl-2-picrylhydrazyl (DPPH). The antimicrobial activity of the essential oil of <em>Cc</em> was evaluated against both gram positive (<em>Bacillus subtilis</em> and <em>Staphylococcus aureus</em>), gram negative (Proteus vulgaris, <em>Pseudomonas aeruginosa</em>) and a pathogenic fungus <em>Candida albicans</em>. <strong>Results:</strong> It was found that <em>Cc </em>afford 0.22% volatile oil. The major components of the volatile oil of <em>Cc</em> are 1, 8-cineol (53.03%), eugenol (12.1%), methyl eugenol (9.2%) and α-pinene (8.3%). The oil had pronounced antibacterial and antifungal activities on all the tested microbes. Nevertheless,<em> Cc</em> leaf oil extract exhibited high antioxidant activity (91.1 ± 0.3 %) at a concentration of 1000 μg.ml<sup>-1</sup>, comparable to 100 μg.ml<sup>-1</sup> gallic acid (95.7 ± 2).</p>}, number={1}, journal={Free Radicals and Antioxidants}, author={I. Abdelhady, Mohamed and A. H. Aly, Hamdy}, year={2020}, month={Dec.}, pages={37–41} }