@article{Kodangala Subraya_Harikiran_Gupta_2012, title={Antioxidant and Anti-inflammatory Activity of Alstonia scholaris R.Br. Stem Bark Extract}, volume={2}, url={https://antiox.org/index.php/fra/article/view/270}, DOI={10.5530/ax.2012.2.2.9}, abstractNote={<p><strong>Background:</strong> The plant <em>Alstonia scholaris</em> R.Br. (Labiatae) is widely cultivated throughout India. The bark of this tree is medicinally used as an astringent, tonic, anthelmintic, antiperiodic and febrifuge. <strong>Methods:</strong> The effect of Methanolic extract of stem bark of <em>Alstonia scholaris</em> R.Br. was investigated to evaluate the antioxidant activity by TLC method and anti-inflammatory activity by Carrageenan induced rat paw odema, dextran induced rat paw odema and cotton pellet induced granuloma.<strong> Result:</strong> Anti-inflammatory activity of the tested extract and its fractions was comparable with that of the standard drug Indomethacin (10 mg/kg).<strong> Conclusion:</strong> The present investigation for the first time, confirms the potential anti-inflammatory activity in the methanol extract of<em> Alstonia scholaris</em> stem bark. Antioxidant property of the extract was confirmed quantitatively by β-carotene–linoleate oxidation method by thin layer chromatography.</p>}, number={2}, journal={Free Radicals and Antioxidants}, author={Kodangala Subraya, Chandrashekar and Harikiran and Gupta, Daksha}, year={2012}, month={Apr.}, pages={55–57} }