TY - JOUR AU - Sundararajan, Raja AU - Koduru, Ravindranadh PY - 2016/01/01 Y2 - 2024/03/29 TI - In vitro antioxidant activity on roots of Limnophila heterophylla JF - Free Radicals and Antioxidants JA - Free Rad. Antiox. VL - 6 IS - 2 SE - Original Article DO - 10.5530/fra.2016.2.8 UR - https://antiox.org/index.php/fra/article/view/92 SP - 178-185 AB - <p><strong>Objective:</strong> The present study was investigating the antioxidant activity of methanol extract of roots of <em>Limnophila heterophylla</em> (Plantaginaceae). Methods: Roots of methanol extract of <em>Limnophila heterophylla</em> were tested for in vitro free radical scavenging assays, such as hydroxyl radical, antioxidant assay by thiocyanate method, inhibition of superoxide anion radical, 2, 2-diphenyl-1-picryl hydrazyl radical (DPPH), lipid peroxidation assay, scavenging of 2, 2’- azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) diammonium salt radical cation assay (ABTS), total antioxidant activity (phosphomolybdic acid method) and reducing ability. <strong>Results:</strong> <em>Limnophila heterophylla</em> roots extract effectively scavenged free radicals at all different concentrations and showed its potent antioxidant activity. Further, these effects were in a dose dependent manner. Results were compared to standard antioxidants such as vitamin E, α-tocopherol, curcumin, quercetin, rutin, butylated hydroxytoluene (BHT), and ascorbic acid. <strong>Conclusion:</strong><em> Limnophila heterophylla</em> enclose strong antioxidant potential. Further the study validates the therapeutic benefits of the Indian system of medicine.</p> ER -